Catalytic promiscuity and the evolution of new enzymatic activities
نویسندگان
چکیده
منابع مشابه
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متن کاملPromiscuity in the Enzymatic Catalysis of Phosphate and Sulfate Transfer
The enzymes that facilitate phosphate and sulfate hydrolysis are among the most proficient natural catalysts known to date. Interestingly, a large number of these enzymes are promiscuous catalysts that exhibit both phosphatase and sulfatase activities in the same active site and, on top of that, have also been demonstrated to efficiently catalyze the hydrolysis of other additional substrates wi...
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ژورنال
عنوان ژورنال: Chemistry & Biology
سال: 1999
ISSN: 1074-5521
DOI: 10.1016/s1074-5521(99)80033-7